Anxious and melancholic depression are followed by differently directed serum albumin conformation

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The aim of the study was investigation of the peculiarities of the conformational changes of serum albumin in patients with anxious and melancholic depression. Albumin conformation was measured by the method of the subnanosecond laser time resolved fluorescence spectroscopy. Anxious depression was followed with the significant decrease of the values of the three amplitudes on the serum albumin in comparison with controls. In the melancholic depression the values of all three amplitudes on serum albumin molecules were significantly elevated in comparison with controls. These results are clearly indicated that anxious and melancholic depression are followed by differently directed changes in serum albumin conformation.

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Sobre autores

M. Uzbekov

Moscow Research Institute of Psychiatry

Autor responsável pela correspondência
Email: uzbekovmg@gmail.com
Rússia, Moscow

N. Smolina

Moscow Research Institute of Psychiatry

Email: uzbekovmg@gmail.com
Rússia, Moscow

T. Syrejshchikova

Moscow Research Institute of Psychiatry

Email: uzbekovmg@gmail.com
Rússia, Moscow

N. Maximova

Moscow Research Institute of Psychiatry

Email: uzbekovmg@gmail.com
Rússia, Moscow

S. Shikhov

Moscow Research Institute of Psychiatry

Email: uzbekovmg@gmail.com
Rússia, Moscow

G. Dobretsov

Moscow Research Institute of Psychiatry

Email: uzbekovmg@gmail.com
Rússia, Moscow

V. Brilliantova

Moscow Research Institute of Psychiatry

Email: uzbekovmg@gmail.com
Rússia, Moscow

V. Krjukov

Moscow Research Institute of Psychiatry

Email: uzbekovmg@gmail.com
Rússia, Moscow

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