Melancholic Depression is Followed by the Increased Serum Nerve Growth Factor Level

封面

如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

The aim of the work was to investigate the nerve grown factor (NGF) level in the blood serum in patients with melancholic depression (MD). The investigated group consists of 23 patients. At admission in the clinic (before any antidepressive treatment) the NGF concentration in patient’s serum was 278.28 ± 43.68 pg/mL that was significantly higher in comparison with controls 239.51 ± 22.15 pg/mL, (p < 0.05), respectively. It is supposed, that the increased NGF level in serum of the MD patients can be connected with the impairment of the functioning of the brain-blood barrier and the increase of its permeability for the NGF.

作者简介

M. Uzbekov

Moscow Research Institute of Psychiatry

Email: nchjournal@gmail.com
Russia, Moscow

S. Shikhov

Moscow Research Institute of Psychiatry

Email: nchjournal@gmail.com
Russia, Moscow

V. Krjukov

Moscow Research Institute of Psychiatry

Email: nchjournal@gmail.com
Russia, Moscow

V. Brilliantova

Moscow Research Institute of Psychiatry

Email: nchjournal@gmail.com
Russia, Moscow

V. Krasnov

Moscow Research Institute of Psychiatry

Email: nchjournal@gmail.com
Russia, Moscow

参考

  1. Краснов В.Н. // Журн. неврологии и психиатрии им. С.С. Корсакова. 2012. Т. 112. Вып. 2. Депрессия. С. 3–11.
  2. Levy M., Boulle F., Steinbusch H., Hove D., Kenis G., Lanfumey L. // Psychopharmacology. 2018. V. 235. P. 2195–2220.
  3. Ciafre S., Ferraguti G., Tiressa P., Iannitelli A., Ralli M., Greco A., Chaldakov G., Rosso P., Fico E., Messina M., CaritoV., Tarani L.,Ceccanti M., Fiore M. // Riv, Psichiatr. 2020. V. 55. P. 4–15.
  4. Sofroniew M., Howe C., Mobley W. // Annu. Rev. Neurosci. 2001. V. 24. P. 1217–1281.
  5. Fiore M., Chaldakov G., Aloe L. // Rev. Neurosci. 2009. V. 20. P. 133–45.
  6. Chaldakov G., Fiore M., Stankulov I. // Prog. Brain Res. 2004. V. 146. P. 279–289.
  7. Chao M. // J. Neurosci. Res. 2000. V. 59. P. 353–355.
  8. Hamilton M. // Handbook of Anxiety Disorders / Eds. Last C., Hersen M. Oxford: Pergamon Press, 1988. P. 143–155.
  9. Rao S., Martínez-Cengotitabengoa M., Yao Y., Guo Z., Xu Q., Li S., Zhou X., Zhang F. // J. Psychiatric Research. 2017. V. 86. P. 39–45
  10. Liu X., Zhang T., He S., Hong B., Peng D., Su H., Li F., Tang Y., Lin Z., Fan Y., Jiang K. // Neuropsychiatr. Dis. Treat. 2014. V. 15. № 10. P. 835–840.
  11. Diniz B., Teixeira A., Machado-Vieira R., Talib L., Gattaz W., Forlenza O. // Am. J. Geriatr. Psychiatry. 2013. V. 21. P. 493–496
  12. Wiener C., Ferreira S., Moreira F., Bittencourt G., Oliveira J., Molina M., Jansen K., Souza L., Lara D., Portela L., Silva R., Oses J. // J. of Affective Disorders. 2015. V. 184. P. 245–248. https://doi.org/10.1016/j.jad.2015.05.067
  13. Guo H., Ren Y., Huang B., Wang J., Yang X., Wang Y. Hindawi Genetics Research. 2022. V. 2022. Article ID 1 097 982. 5 p.
  14. Узбеков М.Г., Шихов С.Н., Крюков В.В., Краснов В.Н., Стрелкова И.М., Узбекова Д.Г. // Сибирский вестник психиатрии и наркологии. 2020. Т. 3. С. 5–10.
  15. Patel J., Frey B. // Neural Plasticity. 2015. V. 2015. Article ID 708306. 12 p.
  16. Morris G., Fernandes B., Puri B., Walker A., Carvalho A., Berk M. // Aust. N Z J. Psychiatry. 2018. V. 52. P. 924–948.
  17. Узбеков М.Г. // Социальная и клиническая психиатрия. 2022. Т. 32. С. 83–87.
  18. Максимова Н.М., Булгакова Т.С., Узбеков М.Г. // Социальная и клиническая психиатрия. 2019. Т. 29. С. 71–77.

补充文件

附件文件
动作
1. JATS XML

版权所有 © М.Г. Узбеков, С.Н. Шихов, В.В. Крюков, В.В. Бриллиантова, В.Н. Краснов, 2023