New synthesis of cycloalca[с]nicotinoamide and nitrile derivatives

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Abstract

Nitriles and amide of nicotinic acid were synthesized by Knoevenagel reactions, nucleophilic vinyl substitution (SNVin), and alkylation. The structure of (1-amino-5-phenyl-5,6,7,8-tetrahydrothieno[2,3- c ]isoquinolin-2-yl)(phenyl)methanone was studied by X-ray analysis.

About the authors

I. V Dyachenko

Lugansk State Pedagogical University

V. D Dyachenko

Lugansk State Pedagogical University

P. V Dorovatovskii

National Research Center “Kurchatov Institute”

V. N Khrustalev

Peoples’ Friendship University of Russia (RUDN University);Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

G. M Abakarov

Dagestan State Technical University

V. G Nenajdenko

Lomonosov Moscow State University

Email: nenajdenko@gmail.com

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