Synthesis and Antioxidant Activity of Alkyl N-(9H-Thioxanthen-9-yl)(cyclo)alkylhydrazides
- Autores: Gorokhov V.Y.1, Zabolotnykh S.A.1, Kharitonova A.V.1, Chekanova L.G.1
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Afiliações:
- Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences
- Edição: Volume 95, Nº 1-2 (2025)
- Páginas: 2-9
- Seção: Articles
- URL: https://modernonco.orscience.ru/0044-460X/article/view/679798
- DOI: https://doi.org/10.31857/S0044460X25010016
- EDN: https://elibrary.ru/AHSQSQ
- ID: 679798
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Resumo
A series of new alkyl N-(9H-thioxanthen-9-yl)(cyclo)alkylhydrazides was obtained for the first time by the reaction of (cyclo)alkylhydrazides, 9H-thioxanthen-9-ol and pyridinium perchlorate in a pyridine medium. The antioxidant activity of alkyl N-(9H-thioxanthen-9-yl)(cyclo)alkylhydrazides was studied. The greatest antioxidant effect was revealed in linear and cyclic N-(9H-thioxanthen-9-yl)(cyclo)alkylhydrazides, the values of which are in the range of 0.72–0.88 from ascorbic acid. The presence of a branched radical in N-(9H-thioxanthen-9-yl)alkylhydrazides significantly reduces the antioxidant properties.
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Sobre autores
V. Gorokhov
Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences
Autor responsável pela correspondência
Email: Gorokhov_V.Yu@mail.ru
ORCID ID: 0000-0003-3829-5038
Rússia, Perm, 614013
S. Zabolotnykh
Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences
Email: Gorokhov_V.Yu@mail.ru
ORCID ID: 0000-0001-8307-0386
Rússia, Perm, 614013
A. Kharitonova
Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences
Email: Gorokhov_V.Yu@mail.ru
ORCID ID: 0000-0002-4791-5799
Rússia, Perm, 614013
L. Chekanova
Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences
Email: Gorokhov_V.Yu@mail.ru
ORCID ID: 0000-0003-1792-6945
Rússia, Perm, 614013
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