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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Modern Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Modern Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Современная онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1815-1434</issn><issn publication-format="electronic">1815-1442</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">26971</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Current algorhytm of screening and early diagnosis of hepatocellular carcinoma</article-title><trans-title-group xml:lang="ru"><trans-title>Современные подходы к скринингу и ранней диагностике гепатоцеллюлярной карциномы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tikhonov</surname><given-names>I N</given-names></name><name xml:lang="ru"><surname>Тихонов</surname><given-names>Игорь Николаевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отд-ния гепатологии клиники пропедевтики внутренних болезней, гастроэнтерологии и гепатологии им. В.Х.Василенко, Университетской клинической больницы №2 ГБОУ вПо Первый МГМУ им. И.М.Сеченова, сотр. научно-образовательного клинического центра инновационной терапии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pavlov</surname><given-names>Ch S</given-names></name><name xml:lang="ru"><surname>Павлов</surname><given-names>Чавдар Савович</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника пропедевтики внутренних болезней, гастроэнтерологии и гепатологии им. В.Х.Василенко, проф., д-р мед. наук, зам. дир. научно-образовательного клинического центра инновационной терапии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mayevskaya</surname><given-names>M V</given-names></name><name xml:lang="ru"><surname>Маевская</surname><given-names>Марина Викторовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>проф. каф. пропедевтики внутренних болезней ГБОУ ВПО Первый МГМУ им. И.М.Сеченова, д-р мед. наук, зав. отд-нием гепатологии клиники пропедевтики внутренних болезней, гастроэнтерологии и гепатологии им. В.Х.Василенко</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ivashkin</surname><given-names>V T</given-names></name><name xml:lang="ru"><surname>Ивашкин</surname><given-names>Владимир Трофимович</given-names></name></name-alternatives><bio xml:lang="ru"><p>акад. ран, проф., д-р мед. наук, зав. каф. пропедевтики внутренних болезней ГБОУ ВПО Первый МГМУ им. И.М.Сеченова, дир. клиники пропедевтики внутренних болезней, гастроэнтерологии и гепатологии им. В.Х.Василенко, главный гастроэнтеролог Минздрава России</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО Первый МГМУ им. И.М.Сеченова Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2014</year></pub-date><volume>16</volume><issue>3</issue><issue-title xml:lang="en">VOL 16, NO3 (2014)</issue-title><issue-title xml:lang="ru">ТОМ 16, №3 (2014)</issue-title><fpage>65</fpage><lpage>74</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://modernonco.orscience.ru/1815-1434/article/view/26971">https://modernonco.orscience.ru/1815-1434/article/view/26971</self-uri><abstract xml:lang="en"><p>The article presents the current possibilities for screening and early diagnosis of hepatocellular carcinoma with imaging techniques, non-invasive serological and immunohistochemical markers, as well as indications and accuracy for morphological study of focal lesions of the liver in patients of risk group.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлены современные положения о возможностях скрининга и ранней диагностики гепатоцеллюлярной карциномы с использованием лучевых методов визуализации, неинвазивных серологических и иммуногистохимических маркеров, а также показания и возможности морфологического исследования очаговых образований печени у пациентов из группы риска.</p></trans-abstract><kwd-group xml:lang="en"><kwd>hepatocellular carcinoma</kwd><kwd>primary liver cancer</kwd><kwd>screening</kwd><kwd>early diagnosis</kwd><kwd>a-fetoprotein</kwd><kwd>biopsy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гепатоцеллюлярный рак</kwd><kwd>первичный рак печени</kwd><kwd>скрининг</kwd><kwd>ранняя диагностика</kwd><kwd>a-фетопротеин</kwd><kwd>биопсия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Amit G. 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