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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Modern Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Modern Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Современная онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1815-1434</issn><issn publication-format="electronic">1815-1442</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">26885</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Xerostomia: a brief look of the problem</article-title><trans-title-group xml:lang="ru"><trans-title>Ксеростомия: краткий взгляд на проблему</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Podvyaznikov</surname><given-names>S O</given-names></name><name xml:lang="ru"><surname>Подвязников</surname><given-names>Сергей Олегович</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф. каф. онкологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГБОУ ДПО Российская медицинская академия последипломного образования Минздрава РФ, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2013</year></pub-date><volume>15</volume><issue>1</issue><issue-title xml:lang="en">NO1 (2013)</issue-title><issue-title xml:lang="ru">ТОМ 15, №1 (2013)</issue-title><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://modernonco.orscience.ru/1815-1434/article/view/26885">https://modernonco.orscience.ru/1815-1434/article/view/26885</self-uri><abstract xml:lang="en"><p>Xerostomia is iatrogenically and non-iatrogenically manifested in patients for a number of reasons and detectable in 12% of the world’s population and its prevalence in the elderly amounts to as much as 25%. Oncologically, xerostomia remains a problem in patients receiving radiotherapy for malignant tumors of the upper respiratory and digestive tracts. The basis for hyposialia prophylaxis is oral hygiene (that is to prevent and treat caries and fungal superinfection). In more complex cases of significant xerostomia, saliva substitutes are used, which give patients instant functional relief.</p></abstract><trans-abstract xml:lang="ru"><p>Ксеростомия проявляется у пациентов по ряду причин ятрогенного и неятрогенного характера и выявляется у 12% жителей планеты, а среди пожилых людей ее распространенность достигает 25%. С онкологических позиций ксеростомия остается проблемой у больных, получающих лучевую терапию по поводу злокачественных опухолей верхних дыхательных и пищеварительных путей. В основе профилактики гипосиалии лежит гигиена полоти рта – профилактика и лечение кариеса и грибковых суперинфекций. В более сложных случаях, при выраженной ксеростомии, используют заменители слюны – мгновенное функциональное облегчение.</p></trans-abstract><kwd-group xml:lang="en"><kwd>xerostomia</kwd><kwd>hyposialia</kwd><kwd>Gougerot–Sjögren syndrome</kwd><kwd>Hyposalix</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ксеростомия</kwd><kwd>гипосиалия</kwd><kwd>синдром Гужеро–Шегрена</kwd><kwd>Гипосаликс</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Guggenheimer J et al. J Am Dent Assos 2003; 13: 61–9.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Altkinson J.C. et al. Dent Clin North AM 2005; 49 (2): 309–26.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Mariette X. Rev Med Intern 2004; 25: 287–93.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Sciubba J.J. et al. Lancet Oncol 2006; 7 (2): 175–83.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Dirix P et al. Cancer 2006; 107 (1): 2525–34.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Gentric-Tilly A et al. Ann Med Intern (Paris) 2002; 153: 378–82.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Novaresh M et al. JADA 2008; 139: 355–405.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Mariette X. Rev Med Intern 2004; 25: 287–93.</mixed-citation></ref></ref-list></back></article>
