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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Modern Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Modern Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Современная онкология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1815-1434</issn><issn publication-format="electronic">1815-1442</issn><publisher><publisher-name xml:lang="en">LLC Obyedinennaya Redaktsiya</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">26679</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Problema prodolzhitel'nosti zhizni bol'nykh zlokachestvennymi opukholyami, poluchayushchikh preparaty-stimulyatory eritropoeza</article-title><trans-title-group xml:lang="ru"><trans-title>Проблема продолжительности жизни больных злокачественными опухолями, получающих препараты-стимуляторы эритропоэза</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pokataev</surname><given-names>I A</given-names></name><name xml:lang="ru"><surname>Покатаев</surname><given-names>И А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tyulyandin</surname><given-names>S A</given-names></name><name xml:lang="ru"><surname>Тюляндин</surname><given-names>С А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">НИИ клинической онкологии РОНЦ им. Н.Н.Блохина РАМН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2007-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2007</year></pub-date><volume>9</volume><issue>2</issue><issue-title xml:lang="en">VOL 9, NO2 (2007)</issue-title><issue-title xml:lang="ru">ТОМ 9, №2 (2007)</issue-title><fpage>39</fpage><lpage>41</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2007, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2007, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://modernonco.orscience.ru/1815-1434/article/view/26679">https://modernonco.orscience.ru/1815-1434/article/view/26679</self-uri><abstract xml:lang="ru"><p>Анемия у больных злокачественными опухолями при проведении химиотерапии – явление частое. Решение этой проблемы представляется актуальным, поскольку анемия не только снижает качество жизни больных, но также, по-видимому, негативно влияет на результаты лечения. Анемия является независимым фактором, свидетельствующим о меньшей продолжительности жизни пациентов, страдающих данным заболеванием, по сравнению с больными, имеющими нормальный уровень гемоглобина [1, 2]. Кроме того, показано, что эффективность химиотерапии и лучевой терапии выше при хорошем кислородном насыщении тканей [3, 4]. До начала 1990-х г. единственным эффективным методом лечения таких больных была гемотрансфузия донорских эритроцитов. С появлением препаратов, стимулирующих эритропоэз (эпоэтин α и β, дарбэпоэтин α), потребность в гемотрасфузиях у таких больных снизилась [5]. Уже почти 15 лет эти препараты используются при лечении анемии у больных, получающих химиотерапию. В последнее время активно обсуждаются вопросы целесообразности использования этих препаратов в качестве профилактики анемии. Представленные научные данные свидетельствуют о том, что препараты, стимулирующие эритропоэз, могут сокращать продолжительность жизни онкологических больных. Выявление подгруппы больных, которым эти препараты назначать нельзя, является задачей дальнейших исследований. Практикующим врачам-онкологам следует учитывать эти данные при планировании лечения анемии.</p></abstract><kwd-group xml:lang="ru"><kwd>онкологические заболевания</kwd><kwd>анемия</kwd><kwd>эритропоэз</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Albain K.S, Crowley J.J, Le Blanc M. Survival determinants in extensive - stage non - small - cell lung cancer: the Southwest Oncology Group experience. J Clin Oncol 1991; 9: 1618–26.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Wagner W, Hermann R, Hartlapp J. 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