Journal of Modern OncologyJournal of Modern OncologyСовременная онкология1815-14341815-1442LLC Obyedinennaya Redaktsiya26637ArticlesСтатьиShort CommunicationKeliks (pegilirovannyy liposomal'nyy doksorubitsin) v programmnoy terapii 2-y linii metastaticheskogo raka molochnoy zhelezyКеликс (пегилированный липосомальный доксорубицин) в программной терапии 2-й линии метастатического рака молочной железы--1503200681VOL 8, NO1 (2006)ТОМ 8, №1 (2006)717309042020Copyright ©; 2006, Consilium MedicumCopyright ©; 2006, ООО "Консилиум Медикум"2006Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc/4.0https://modernonco.orscience.ru/1815-1434/article/view/26637

Несмотря на доступность целого ряда новых противоопухолевых препаратов, антрациклины сохраняют свое важнейшее место в терапии больных МРМЖ. Однако применение доксорубицина ограничено его токсическими эффектами и, прежде всего развитием кумулятивной кардиотоксичности. Новый противоопухолевый препарат «Келикс» - пегилированный липосомальный доксорубицин - убедительно продемонстрировал эффективность в многоцентровых рандомизированных исследованиях III фазы у больных МРМЖ, как в 1-й линии, так и при резистентности к традиционным антрациклинам и таксанам.

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