The pathogenetic aspects of vaginal dysbiosis and the current possibilities of its correction


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Abstract

The review presents the data currently available in the literature, including the authors’ publications, regarding the pathogenetic aspects of vaginal dysbiosis. It discusses the role of gram-negative bacterial lipopolysaccharides in the development of bacterial vaginosis. The paper provides a rationale for the pathogenetic correction of vaginal dysbiosis through the local and oral use of probiotic L. crispatus, L. brevis, and L. acidophilus strains.

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About the authors

Karina Rustamovna Bondarenko

N.I. Pirogov Russian National Research Medical University

Email: karinabond@mail.ru
PhD, assistant of the Department of Obstetrics and Gynecology № 1

Lyudmila Anatolevna Ozolinya

N.I. Pirogov Russian National Research Medical University

Doctor of Medicine, Professor of the Department of Obstetrics and Gynecology № 1

Victor Mihajlovich Bondarenko

N.F. Gamaleya Research Institute of Epidemiology and Microbiology

Email: bvmz@yandex.ru
Doctor of Medicine, Professor, Head of Genetics of Bacterial Virulence Laboratory

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